In late 2002, Murphy began dating Ashton Kutcher, her co-star in Just Married. Once engaged to talent manager Jeff Kwatinetz, Murphy became engaged to Joe Macaluso in December 2005, a production assistant she met while working on the film Little Black Book. In August 2006, they ended their engagement. In May 2007, Murphy married British screenwriter Simon Monjack in a private Jewish ceremony in Los Angeles. For the last three and a half years of her life, Murphy, her mother and Monjack lived in the same house together.